Attempted to read or write protected memory. This is often an indication that other memory has been corrupted.

Hit below error when deploy a new app to existing running application.

Attempted to read or write protected memory. This is often an indication that other memory has been corrupted. 
Description: An unhandled exception occurred during the execution of the current web request. Please review the stack trace for more information about the error and where it originated in the code. 


Exception Details: System.AccessViolationException: Attempted to read or write protected memory. This is often an indication that other memory has been corrupted. 



Source Error: 


An unhandled exception was generated during the execution of the current web request. Information regarding the origin and location of the exception can be identified using the exception stack trace below.


Try to set the folder permission but still hit the same error after restart iis. 


Next, i try to run the permissions wizard in the IIS. After run it, restart iis and i'm lucky. It work like normal.

Hope this help.